Let's Explore SEMGLEE®

Let's Explore SEMGLEE®

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If you are an adult with type 1 diabetes or type 2 diabetes, or an adult caretaker of a pediatric patient (children 6 years and older) with type 1 diabetes, talk to your doctor about SEMGLEE.

  • Bell Icon
    SEMGLEE (insulin glargine-yfgn) is the first interchangeable biosimilar insulin product approved in the United States. SEMGLEE is indicated to improve glycemic control in adults and pediatric patients with Type 1 diabetes mellitus and in adults with Type 2 diabetes mellitus. SEMGLEE is both biosimilar to, and interchangeable with, its reference product LANTUS (insulin glargine), a long-acting insulin analog. This means that SEMGLEE may be substituted for LANTUS at the pharmacy, subject to state pharmacy laws.
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    SEMGLEE is available as a prefilled pen with 3 mL solution containing 100 units/mL (U-100) insulin glargine.1
    The pen is designed to be used for multiple subcutaneous injections with single-use disposable needles.1
  • Shield IconSEMGLEE is not for use in treating diabetic ketoacidosis.1
    It is not known if SEMGLEE is safe and effective in children younger than 6 years with type 1 diabetes.1
  • Insulin Pen and Product Vial Package
SEMGLEE Prefilled Pen Instructions for use

 

 
Detailed Product Pen Image

UNDERSTANDING DIABETES

 
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Diabetes is common in the United States.2

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Among people who have been identified as having diabetes, more than 1 in 4 people are not aware that they have this condition.2

Adult and Child
 

Diabetes can affect anyone: children and adults of any age.2

WHAT IS DIABETES?

Plate of Healthy Food
 
 
 

Diabetes is a condition that occurs when glucose, also called blood sugar, is too high. Glucose is your main source of energy and comes from the food you eat. Insulin, a hormone made by the pancreas, is needed to transfer this glucose from your blood to your cells to be converted into energy.2

 

Sometimes your body doesnt make enough, or any, insulin. When this happens, glucose stays in your blood without reaching your cells.2

Image of Pancreas
 
 
Blood Cells
 
 
 

When someone experiences high blood glucose levels due to a lack of insulin, diabetes can develop.
Over time, having too much glucose in your blood can cause health problems, including heart disease, nerve damage, eye problems, and kidney disease. You can take various measures to prevent or manage diabetes.2

WHAT ARE THE DIFFERENT TYPES OF DIABETES?

TYPE 1 DIABETES2

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  • If you have type 1 diabetes, your body does not produce insulin on its own because your immune system attacks and destroys the cells in your pancreas that make insulin
  • Type 1 diabetes is usually diagnosed during childhood or during the teenage years, although it can appear at any age
  • Having a parent or a sibling with type 1 diabetes might increase the chance of developing type1 diabetes

TYPE 2 DIABETES2

  • If you have type 2 diabetes, your body does not make or use insulin enough to produce energy
  • You can develop type 2 diabetes at any age, even during childhood. However, this type of diabetes occurs most often in middle-aged and older adults
  • Risk factors for type 2 diabetes include a family history of diabetes or obesity
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If you have been diagnosed with Type 1 or Type 2 Diabetes, talk to your doctor about the best way to manage it, including whether insulin is an appropriate option for you.2

THE IMPORTANCE OF INSULIN

 

Insulin is a hormone made by the pancreas that helps transfer the glucose in the food you eat from your blood to the cells in your muscles, fat, and liver, where it is used for energy.

IN TYPE 1 DIABETES2:

  • Image of Pancreas The pancreas cannot or has stopped producing insulin.
  • Insulin Pen People with type 1 diabetes need to take daily insulin shots, along with maintaining a healthy diet and regular exercise routine, to manage the disease.

IN TYPE 2 DIABETES2:

  • Pull Off The Pen Cap The pancreas doesn't produce enough insulin or the body doesn't use it efficiently.
  • Pull Off The Pen Cap People with type 2 diabetes may need to manage their condition with insulin shots or other drugs, along with maintaining a healthy diet and a regular exercise routine, as directed by their doctor.

 

References:

  1. SEMGLEE (insulin glargine-yfgn) injection. Prescribing Information. 2023. Biocon Biologics Inc. Cambridge, MA.
  2. National Institute of Diabetes and Digestive and Kidney Diseases. What is Diabetes?
    Accessed August 11, 2023.
    https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes